간행물열람

한국생체재료학회에 오신 것을 환영합니다.
home > 간행물 > 간행물열람
학회지 및 기타 간행물의 열람 제한
  • 홈페이지상에서 학회지 및 기타 간행물의 열람 및 다운로드가 가능합니다.
  • 이하의 게시물은 홈페이지의 실명으로 회원가입하신 후 학회회원임이 확인되신 경우 로그인 후 열람이 가능합니다. 궁금한 점은 생체재료학회 사무국(e-mail : ksbm2011@naver.com) 으로 문의하시기 바랍니다.
제목 [한국생체재료학회지] 제 22권 4호 290-302
작성자 관리자 등록일 2019-01-10
첨부파일

Background: The main purpose of drug delivery systems is to deliver the drugs at the appropriate concentration to the precise target site. Recently, the application of a thin film in the field of drug delivery has gained increasing interest because of its ability to safely load drugs and to release the drug in a controlled manner, which improves drug efficacy. Drug loading by the thin film can be done in various ways, depending on type of the drug, the area of exposure, and the purpose of drug delivery. Main text: This review summarizes the various methods used for preparing thin films with drugs via Layer-by-layer (LbL) assembly. Furthermore, additional functionalities of thin films using surface modification in drug delivery are briefly discussed. There are three types of methods for preparing a drug-carrying multilayered film using LbL assembly. First methods include approaches for direct loading of the drug into the pre-fabricated multilayer film. Second methods are preparing thin films using drugs as building blocks. Thirdly, the drugs are incorporated in the cargo so that the cargo itself can be used as the materials of the film. Conclusion: The appropriate designs of the drug-loaded film were produced in consideration of the release amounts and site of the desired drug. Furthermore, additional surface modification using the LbL technique enabled the preparation of effective drug delivery carriers with improved targeting effect. Therefore, the multilayer thin films fabricated by the LbL technique are a promising candidate for an ideal drug delivery system and the development possibilities of this technology are infinite.
 

Key words : Layer-by-layer assembly, Multilayer thin films, Controlled drug delivery, Surface modification
 

[ 논문 다운로드]